Journal of
Systemics, Cybernetics and Informatics
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ISSN: 1690-4524 (Online)


Peer Reviewed Journal via three different mandatory reviewing processes, since 2006, and, from September 2020, a fourth mandatory peer-editing has been added.

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Published by
The International Institute of Informatics and Cybernetics


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Academia.edu
(A Community of about 40.000.000 Academics)


Honorary Editorial Advisory Board's Chair
William Lesso (1931-2015)

Editor-in-Chief
Nagib C. Callaos


Sponsored by
The International Institute of
Informatics and Systemics

www.iiis.org
 

Editorial Advisory Board

Quality Assurance

Editors

Journal's Reviewers
Call for Special Articles
 

Description and Aims

Submission of Articles

Areas and Subareas

Information to Contributors

Editorial Peer Review Methodology

Integrating Reviewing Processes


Utilization of Artificial Intelligence by Students in Interdisciplinary Field of Biomedical Engineering
Shigehiro Hashimoto
(pages: 1-5)

Transdisciplinary Applications of Data Visualization and Data Mining Techniques as Represented for Human Diseases
Richard S. Segall
(pages: 6-15)

Beyond Status Quo: Why is Transdisciplinary Communication Instrumental in Innovation?
James Lipuma, Cristo Leon
(pages: 16-20)

How We Can Locate Validatable Foundations of Life Themes
Jeremy Horne
(pages: 21-32)

Bringing Discipline into Transdisciplinary Communications -The ISO 56000 Family of Innovation Standards-
Rick Fernandez, William Swart
(pages: 33-39)

To AI Is Human: How AI Tools with Their Imperfections Enhance Learning
Martin Cwiakala
(pages: 40-46)

Knowledge, Learning and Transdisciplinary Communication in the Evolution of the Contemporary World
Rita Micarelli, Giorgio Pizziolo
(pages: 47-52)

Human Complexity vs. Machine Linearity: Tug-of-War Between Two Realities Coexisting in Precarious Balance
Paolo Barile, Clara Bassano, Paolo Piciocchi
(pages: 53-62)

A Cybernetic Metric Approach to Course Preparation
Russell Jay Hendel
(pages: 63-70)

The Impact of Artificial Intelligence on Education
John Jenq
(pages: 71-76)

Bridging the Gap: Harnessing the Power of Machine Learning and Big Data for Media Research
Li-jing Arthur Chang
(pages: 77-84)

Image Processing, Computer Vision, Data Visualization, and Data Mining for Transdisciplinary Visual Communication: What Are the Differences and Which Should or Could You Use?
Richard S. Segall
(pages: 85-92)

Identification – The Essence of Education
Jeremy Horne
(pages: 93-99)

The Greek-Roman Theatre in the Mediterranean Area
Maria Rosaria D’acierno Canonici Cammino
(pages: 100-108)

Examination of AI and Conventional Teaching Approaches in Cultivating Critical Thinking Skills in High School Students
Luis Castillo
(pages: 109-112)

Thoughts, Labyrinths, and Torii
Maurício Vieira Kritz
(pages: 113-119)

Can Two Human Intelligences (HIs or Noes) and Two Artificial Intelligences (AIs) Get Involved in Interlinguistic Communication? – A Transdisciplinary Quest
Ekaterini Nikolarea
(pages: 120-128)


 

Abstracts

 


ABSTRACT


Measurement of Contractile Force of Myotube on Scaffold of Thin Film with Micro-Pattern-Markers

Yusuke Takahashi, Shigehiro Hashimoto, Kenta Sugimoto, Daiki Watanabe, Haruka Hino


A scaffold of a transparent film with micro pattern markers has been designed to measure the contractile force of myotube under electric stimulation in vitro. The scaffold is made of a thin film (thickness 0.006 mm), of which the back side has arrangement of polydimethylsiloxane micro-protrusions (0.004 mm diameter, 0.002 mm height, 0.003 mm interval) made by the photolithography technique. C2C12 (mouse myoblast) was seeded on the film at the counter surface to the protrusions at the density of 50000 cells/cm2. The cells were cultured on the scaffold for 12 days in the medium containing 10% FBS (fetal bovine serum) and 1% penicillin/ streptomycin at 310 K with 5% of CO2 content. The electric pulses (amplitude of 30 V (0.06 A) ; pulse cycle of 1 s; pulse width of 1 ms) were applied between electrodes of the titanium wire dipped in the medium. The contraction of myotubes is able to be observed through the transparent scaffold at the microscope. The contractile force of myotube at the electric stimulation estimated by the deformation of the film was 10-4 N. The designed scaffold has a potential for the measurement of the local contractile force of the myotube microscopically in vitro.

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