Journal of
Systemics, Cybernetics and Informatics
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ISSN: 1690-4524 (Online)


Peer Reviewed Journal via three different mandatory reviewing processes, since 2006, and, from September 2020, a fourth mandatory peer-editing has been added.

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Published by
The International Institute of Informatics and Cybernetics


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Honorary Editorial Advisory Board's Chair
William Lesso (1931-2015)

Editor-in-Chief
Nagib C. Callaos


Sponsored by
The International Institute of
Informatics and Systemics

www.iiis.org
 

Editorial Advisory Board

Quality Assurance

Editors

Journal's Reviewers
Call for Special Articles
 

Description and Aims

Submission of Articles

Areas and Subareas

Information to Contributors

Editorial Peer Review Methodology

Integrating Reviewing Processes


How Does Logical Dynamics Assist Interdisciplinary Education and Research in Addressing Cognitive Challenges?
Mengqin Ning, Jiahong Guo
(pages: 1-6)

Inter-Corrective Meta-Dialogue on Constructive Impact of Trans-disciplinary Communication in Modern Education
Vinod Kumar Verma
(pages: 7-9)

Intergenerational Learning for Older and Younger Employees: What Should Be Done and Should Not?
Gita Aulia Nurani, Ya-Hui Lee
(pages: 10-15)

On the Ontological Notion of Education
Jeremy Horne
(pages: 16-24)

Research-Based Learning in Intergenerational Dialogue and Its Relationship to Education
Sonja Ehret
(pages: 25-29)

Role-Playing in Education: An Experiential Learning Framework for Collaborative Co-design
Cristo Leon, James Lipuma, Sirimuvva Pathikonda, Rafael Arturo Llaca Reyes
(pages: 30-38)

The Emergent Role of Artificial Intelligence as Tool in Conducting Academic Research
Bilquis Ferdousi
(pages: 39-46)

The Impact of Cybernetic Relationships Between Education and Work-Based Learning
Birgit Oberer, Alptekin Erkollar
(pages: 47-51)

The Notions of Education and Research
Nagib Callaos, Jeremy Horne
(pages: 52-62)

Towards Sustainable Legal Education Reform: Interdisciplinary and Transdisciplinary Approaches in Albania's Justice System
Adrian Leka, Brunilda Haxhiu
(pages: 63-67)

Transdisciplinary Research and the Gift Economy
Teresa Henkle Langness
(pages: 68-75)


 

Abstracts

 


ABSTRACT


Measurement of Contractile Force of Myotube on Scaffold of Thin Film with Micro-Pattern-Markers

Yusuke Takahashi, Shigehiro Hashimoto, Kenta Sugimoto, Daiki Watanabe, Haruka Hino


A scaffold of a transparent film with micro pattern markers has been designed to measure the contractile force of myotube under electric stimulation in vitro. The scaffold is made of a thin film (thickness 0.006 mm), of which the back side has arrangement of polydimethylsiloxane micro-protrusions (0.004 mm diameter, 0.002 mm height, 0.003 mm interval) made by the photolithography technique. C2C12 (mouse myoblast) was seeded on the film at the counter surface to the protrusions at the density of 50000 cells/cm2. The cells were cultured on the scaffold for 12 days in the medium containing 10% FBS (fetal bovine serum) and 1% penicillin/ streptomycin at 310 K with 5% of CO2 content. The electric pulses (amplitude of 30 V (0.06 A) ; pulse cycle of 1 s; pulse width of 1 ms) were applied between electrodes of the titanium wire dipped in the medium. The contraction of myotubes is able to be observed through the transparent scaffold at the microscope. The contractile force of myotube at the electric stimulation estimated by the deformation of the film was 10-4 N. The designed scaffold has a potential for the measurement of the local contractile force of the myotube microscopically in vitro.

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