Cell Sorting Using Diagonal Bottom Grooves in a Microchannel
Kota Yamamoto, Shigehiro Hashimoto
Cell shape is related to cell function. For the purpose of cell sorting based on shape, a channel with diagonal grooves on the bottom was designed. A cell suspension was poured into a channel created by micromachining, and cell sorting according to shape was confirmed. Experimental results shows that smaller and more elongated cells undergo a larger shift perpendicular to the mainstream direction during passing over the groove. Diagonal bottom grooves in a microchannel are effective for cell sorting. Full Text
|