A Predictive and Preventative Computation for the Diagnosis of the Heartbeat Control Systems: DFA for the Risk of Mortality in Both, Animal Models and Humans
Toru Yazawa, Katsunori Tanaka, Tomoyuki Nagaoka, Tomoo Katsuyama
We analyzed the heartbeat interval by the detrended
fluctuation analysis (DFA) in models and humans. In
models, the myocardium of the healthy heart contracted
regularly. The deteriorated heart model, however, showed
alternating beats so-called “alternans.” The DFA revealed
that if the heart is having “alternans” exhibited there is a
declined scaling exponent (~0.5). In humans, the heart
that had “alternans” also showed a low scaling exponent
(~0.6). We consider that the coexistence of “alternans”
and a low scaling exponent can be a risk marker in
predictive and preventative diagnosis, supporting the idea
that “alternans” can be a harbinger of sudden death. Full Text
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